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Discussion > Covid 19 stuff

If you are admitted to hospital, don’t take hydroxychloroquine, It doesn’t work.

- Martin Landray, Professor of medicine and epidemiology at Oxford University.

Clearly Trump-Deranged.

Source

Then there's this randomised, double-blind trial.

After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid-19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure.

https://www.nejm.org/doi/full/10.1056/NEJMoa2016638

We know this drug is effective against Lupus and Rheumatoid Arthritis. Against COVID, not so much. Promoting an unproven remedy as a 'game-changer' during a pandemic and causing a spike in demand is irresponsible. I am simply amazed this needs to be repeated, but here we are…..

Jun 5, 2020 at 10:36 PM | Unregistered CommenterPhil Clarke

You're easily amazed - but then we all know that.

Tangerine Trump Terrible

The 3T virus

I think I prefer Dr. Phil Hammond over Dr. Phil Clarke

Jun 5, 2020 at 11:00 PM | Registered Commentertomo

Jun 5, 2020 at 10:36 PM Phil Clarke

Your snark about Hydroxychloroquine predates the article you quote now, and the debunked Report in The Lancet.

Who pumped you full of mistrust about Hydroxychloroquine and when? You never quoted a source.

Jun 5, 2020 at 11:21 PM | Unregistered Commentergolf charlie

Look at the doses used in the Oxford study:

https://twitter.com/JaclynHord/status/1269046685625470976

Long interview, but worth it:

https://evidencenotfear.com/professor-dolores-cahill-james-delingpole-channel/

Jun 6, 2020 at 2:47 PM | Unregistered CommenterCharly

Clarkey, there is a word missing from that NEJM piece. Can you work out what it is?

Jun 6, 2020 at 2:55 PM | Unregistered CommenterCharly

HCQ trials designed to fail?

https://www.newindianexpress.com/nation/2020/may/29/icmr-writes-to-who-disagreeing-with-hcq-assessment-officials-say-international-trial-dosage-four-ti-2149702.amp

Jun 6, 2020 at 3:04 PM | Unregistered CommenterCharly

2400mg in the first 24 hours!

https://www.recoverytrial.net/files/recovery-protocol-v6-0-2020-05-14.pdf

Jun 6, 2020 at 3:13 PM | Unregistered CommenterCharly

More on the Oxford study -

http://covexit.com/uk-recovery-trial-inadequate-hydroxychloroquine-treatment-predictably-fails/

Criminal behaviour.

Jun 6, 2020 at 3:25 PM | Unregistered CommenterCharly

"If you are admitted to hospital, don’t take hydroxychloroquine, It doesn’t work."
- Martin Landray, Professor of medicine and epidemiology at Oxford University.

Actually this quotation, brought to us by Phil, would appear to be acceptable to all - those supporting use of hydroxychloroquine and those opposed to its use. By the time a patient has been admitted to hospital with, mostly, well developed symptoms, it's acknowledged by even its most ardent supporters to be too late to be effective. Furthermore the medication can have unwanted side effects. In the medication trial I took part in, I wouldn't have been allowed to trial HQ because of my prior history of heart arrhythmia.

Jun 6, 2020 at 4:24 PM | Unregistered CommenterAK

AK, the NHS advice is "if you get ill, self-isolate, stay home." I remember you posted a question on what kinds of 'flu were doing the rounds. How long was the period between you becoming ill and hospitalisation or other treatment/medication?

The Oxford study talks of "post-infection prophylactic" use of HCQ. For Heaven's sake!

Jun 6, 2020 at 7:05 PM | Unregistered CommenterCharly

Charly in my case probably more than three weeks. The reason I cannot give a firm answer is that for a time (according to she who should be listened to, more than a week) I was completely lethargic and I don't remember much of that period. In the initial stages I was quite convinced I didn't have Covid19 because, although I felt increasing ill, I never developed a cough and the fever came on so slowly. I became convinced I was suffering from a regular flu (hence my question to BH regulars).
Sorry not to be more precise. I still cannot reconcile my illness history (or what I can recall about it) with the normal progression and timing of Covid19 attacks that I read about. Yet I had a positive test for the virus at the hospital. Without that I could have convinced myself that I had a severe regular flu with added bacterial pneumonia complications.

Jun 6, 2020 at 7:54 PM | Unregistered CommenterAK

Given that Covid19 is a virus, and we know a bit about its cell entry mechanism, enough it seems to indicate that the progress of an infection is not going to present as a firm shopping list of symptoms that have been promulgated largely via the MSM.

The quality of an individual's immune response seems even more important now, six months down the road. Dr Seheult's piece from March is still imho worth a watch wrt to boosting immune response (the Kelloggs Cornflakes and Spanish Flu part is a bonus).

Jun 6, 2020 at 8:49 PM | Registered Commentertomo

oops timed out...

The quality of an individual's immune response seems even more important now, six months down the road. Dr Seheult's piece from March is still imho worth a watch wrt to boosting immune response (the Kelloggs Cornflakes and Spanish Flu part is a bonus).

Are there immune system features (or lack of features beyond "not knowing the specific virus") in those succumbing to the virus that precipitate a bad reaction? It is very clear that older people with a less active immune response are at risk and the cytokine storm thing is a nasty feature of some immune responses.

Viruses can be rather random in what they do in a host depending on their method of cell entry. Some years ago an uncle of mine was paralysed and on a ventilator for about a week - he survived and took a couple of months to recover - the medics treating him told my aunt "it's probably a virus in his nervous system".

Jun 6, 2020 at 9:09 PM | Registered Commentertomo

AK, over 3 weeks is a very long time. For the virus to replicate, and for a bacterial infection to take hold.

What were the doctors doing?

"Testing. Testing. Testing!" But no plans on what to do, even if the information is accurate.

Test the state of the patient's immune system? Don't be silly.

Jun 6, 2020 at 10:00 PM | Unregistered CommenterCharly

I see the HCQ trolls are piling into Dr. Zelenko

Jun 8, 2020 at 12:38 AM | Registered Commentertomo

TDS + PC = MSN = Fake News

Jun 10, 2020 at 5:46 PM | Unregistered CommenterIantanyrallt

if you were wondering about the makeup of SAGE

Jun 11, 2020 at 12:55 PM | Registered Commentertomo

copied here to avoid wrestling with searching "unthreaded"

I came across this podcast (linked to by Matt Ridley) which is blissfully low hysteria imho covering some Covid-19 territory that's been forced onto the back burner.

Jun 11, 2020 at 6:28 PM | Registered Commentertomo

Things you won't see on the BBC / MSM....

U.S. National Institutes of Health Fires 54 Researchers As Ongoing Investigation Reveals 93% Failed to Disclosed Links to Chinese Communist Party

here

Jun 15, 2020 at 10:06 PM | Registered Commentertomo

Wuhan Institute of Virology has been under People's Liberation Army control since February 7th.

Jun 16, 2020 at 9:48 AM | Registered Commentertomo

Chinese Enlish language state media is claiming that the coronavirus is killing 100 time more people in the USA versus China.

We don't really get to see what they are telling their own population in the local lingo.

Near zero coverage by western media about the purported second wave that's disrupting Beijing (but not, a bit perversely international flights....)

elsewhere

Dexamethasone

Jun 17, 2020 at 6:08 AM | Registered Commentertomo

anecdotal - Chinese government now seemingly has a thing about harassing "foreigners"

elsewhere

Forecasting is hard

Jun 17, 2020 at 7:10 AM | Registered Commentertomo

I see reports that the BBC is now accusing people who challenge the official mortality statistics and talk about the virus maybe having escaped from a laboratory of being mentally ill.

By that measure Dr. Niel Ferguson should only be allowed out dressed in Dr. Hannibal Lecter's prison kit.

Jun 19, 2020 at 11:36 AM | Registered Commentertomo

Phil Clarke still in radio silence mode.

Jun 19, 2020 at 6:07 PM | Unregistered CommenterCharly